In a new study published in The Journal of Clinical Endocrinology & Metabolism (JCEM) from Oxford Academic, “Habitual Coffee, Tea, and Caffeine Consumption, Circulating Metabolites, and the Risk of Cardiometabolic Multimorbidity,” consumers of moderate amounts of caffeine had the lowest risk for Cardiometabolic Multimorbidity (CM). CM is one of the most common and harmful multimorbidity profiles and is defined as the coexistence of two or three cardiometabolic diseases, including diabetes, coronary heart disease, and stroke.
According to the study, compared with nonconsumers or consumers of less than 100 mg caffeine per day, consumers of moderate amount of coffee (3 drinks/d) or caffeine (200-300 mg/d) had the lowest risk for new-onset CM, with respective hazard ratios (95% CIs) of 0.519 (0.417-0.647) and 0.593 (0.499-0.704).
The study’s Conclusion follows.
Conclusion
Habitual coffee or caffeine intake, especially at a moderate level, was associated with a lower risk of new-onset CM and could play important roles in almost all transition phases of CM development. Future studies are warranted to validate the implicated metabolic biomarkers underlying the relation between coffee, tea, and caffeine intake and CM.