Publishing in the journal, Parkinsonism & Related Disorders, researchers used a nested case-control study design to evaluate the impact of antimicrobial exposure on the risk of developing Parkinson’s disease (PD), a movement disorder that manifests as tremors, stiffness, and balance issues. The study found that in a large UK-representative population, the risk of PD was modestly lower among adults who had previously received multiple courses of penicillins in the last 15 years, and modestly higher among those exposed to antifungal medicines in recent years.
Highlights of the study follow.
Highlights
Studies have explored how antimicrobial use alters the gut microbiome and Parkinson’s disease (PD) risk.
The relationship between antimicrobial exposure and PD risk was studied using the Clinical Practice Research Datalink (CPRD).
PD risk was lower among adults who received penicillins and higher among those exposed to antifungal medicines.